Repligen Day of Innovation - Fribourg, Switzerland

Thurs. September 5, 2024 

Biofactory Competence Center (BCC)
Pass. du Cardinal 13b,
1700 Fribourg, Switzerland

You are invited to join the Repligen Day of Innovation (RDI) on Thursday 5th September, at the Biofactory Competence Center (BCC) Fribourg, Switzerland, where we will showcase live the new KrosFlo® KR2i RPM™ System, the CTech™ SoloVPE® System, and the recently launched KrosFlo® RS 10.

The KrosFlo® KR2i RPM™ System is the first automated UFDF system using Variable Pathlength Spectroscopy Inline analytics for process control, where as the SoloVPE is the AtLine technology that can measure up to 300 mg/ml (mAbs) without dilution or signal saturation, and <2% RSD.  We will use a recombinant protein for each live demonstration.    

The KrosFlo® RS10 is the first bench scale TFF system built specifically for cGMP production with true end to end automation. Designed as a single standardized platform and not as a standalone system, the KrosFlo® RS10 shares the same industrial grade components and automation capabilities as the entire RS systems series from 0.1m2 to 20m2.

Lunch and refreshments will be provided. The event is free of charge, but registration is required. 
The number of attendees is limited. Registration deadline is 23rd August 2024.

What will you learn:

  • Intro into Variable Pathlength Technology (VPT) and real-time monitoring of concentration
  • How to perform a PAT-driven UF/DF process 
  • How to remove sample prep and dilutions for product concentrations up to 300mg/ml using the CTech SoloVPE
  • How Slope Spectroscopy can be implemented for multiple modalities – ADCs, mAbs, mRNA, plasmids, DNA/Oligos, AAV….
  • How end-to-end automation of TFF processes reduc

Who should attend:

  • Tangential Flow Filtration users
  • Downstream Process specialists
  • Process Development specialists
  • MSAT and/or Manufacturing specialists
  • Analytical Development and QC

Agenda

   Time
 
  Session
 

  9:30 AM     Welcome: registration & coffee


  9:45 AM     Introduction to Repligen


10:00 AM     CTech SoloVPE - Live hands-on demonstration


11:15 PM     KrosFlo KR2i RPM (automated UFDF) - Live hands-on demonstration


12:30 PM     Lunch


13:30 PM    KrosFlo RS10 TFF - Live hands-on demonstration

15:00 PM    Q&A, End, Refreshments

 

Register Today